Published Date: 2000-06-15 23:50:00
Subject: PRO> Hand, foot and mouth disease - South Korea: comment
Archive Number: 20000615.0969

HAND, FOOT AND MOUTH DISEASE - SOUTH KOREA: COMMENT
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A ProMED-mail post
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See Also

Enterovirus 71 - South Korea (Cheju-do) 2000.1779
1999
----
Enterovirus 71, fatal - China (Hong Kong) 19990523213449, 19990525232553
Enterovirus 71, fatal - China (Hong Kong) (02) 19990605201705
Enterovirus 71, treatment - Japan 19990711160807
Enterovirus 71 - Asia 19991226225820
Enterovirus 71 - Australia (Western)(02) 19990628122119
Enterovirus 71 - Australia (Western) (03) 19990730152336
Enterovirus 71 - Australia: RFI 19990627205115
Enterovirus 71 - Taiwan 1998: clinical signs 19990821234913
Enterovirus 71 genotypes - Malaysia, Japan, Taiwan... 19990821212226
Date: 15 Jun 2000
From: T. G. Yap <tgyap@pc.jaring.my>

With report of new cases of hand, foot and mouth disease [HFMD in Korea,
it might be wise for investigators to keep an open mind and to avoid
falling into what I called the "EV71 paradigm". I have written an article
entitled, "EV71 or Adenovirus? Hypothesis arising from two epidemics
spanning 1997-1998", in which I laid out reasons for believing that a new
strain of adenovirus was the more likely culprit virus for causing
deaths.It was published in the Newsletter of the Malaysian Medical
Association and obtainable at <http://www.geocities.com/vadivale/> [Dr.
Vadivale's excellent web site -
Mod. CHC.
--
TG Yap
Clinical Sciences Department,
International Medical University
Bukit Jalil, Kuala Lumpur.
<tgyap@imu.edu.my>
[Jack Woodall received notice of the paper mentioned above and tried to
obtain permission to post an abstract of it. When a few days passed and the
story seemed "cold" to us, we decided to not pursue this further. There has
been considerable controversy regarding the etiology of the severe
outbreaks of HFMD and apparent central nervous system complications in
southeast Asia, attributed by some to enterovirus 71 and to other to a
newly discovered adenovirus. Good people on each side of this contentious
argument are convinced of opposing viewpoints. Needless to say, we cannot
draw reasonable conclusions from this distance. Rather than comment one way
or the other, we recommend that interested readers go to the web site and
read for themselves Dr. Yap's paper and other papers. - Mod. CHC
.....................................................jw/chc/ds
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