Published Date: 2002-06-17 23:50:00
Subject: PRO> Norwalk-like virus, decontamination methods (02)
Archive Number: 20020617.4519
NORWALK-LIKE VIRUS, DECONTAMINATION METHODS (02)
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Date: Mon 17 Jun 2002
From: Marc-Alain Widdowson <zux5@cdc.gov>
Another Thought on Norwalk-like Virus Decontamination
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[This useful additional comment requires me to reinstate this thread which
I had cut prematurely. - Mod.CP]
There is a real gap in knowledge of which disinfectants (apart from very
high concentrations of sodium hypochlorite (bleach) solution) can be used to
decontaminate the environment in protracted "person-to-person" outbreaks of
Norwalk-like viruses so often a problem in cruise ships.
A recent paper (2001) in the Journal of Food Protection (Gulati et al: 4
(9) 1430-4) uses feline calicivirus as a model for Norwalk-like viruses.
The evidence presented suggests that phenolic compounds at concentrations
of twice the manufacturer's recommendations (which are 1:256 dilution of
4.25 percent o-benzyl p-chlorophenol and 4.75% o-phenylphenol) might be the
most effective disinfectant against Norwalk-like viruses. This compares
with sodium hypochlorite, which even at concentrations of 800 ppm was not
particularly effective.
I don't, however, know the effects of phenolics on soft furnishings.
--
Marc-Alain Widdowson MA VetMB MSc
Viral Gastroenteritis Section
Respiratory and Enteric Viruses Branch
Centers for Disease Control and Prevention
1600 Clifton Road NE
Atlanta, GA 30333
<zux5@cdc.gov>
See Also
Norwalk-like virus, decontamination: RFI 20020612.4475Norwalk-like virus, decontamination methods 20020615.4497
Norwalk-like virus, cruise ship - USA (Alaska) 20020607.4432
Norwalk-like virus, cruise ship - USA (Alaska) (02) 20020610.4462
Norwalk-like virus, hosp. outbreak - UK (Scot.) (03) 20020123.3365
Norwalk-like virus, hospital o/b - UK (London) (02) 20020530.4364
Norwalk-like virus, hospital outbreak - UK (England) 20020607.4434
Norwalk-like virus, hospital outbreak - UK (London) 20020528.4339
Norwalk-like virus, hospital outbreak - UK (Scot.)... 20020120.3333
Norwalk-like virus, hospital outbreak - UK (Scotla... 20020126.3409
Norwalk-like virus, hospital outbreak - UK (Scotland) 20020119.3323
Norwalk-like virus, outbreaks - UK 20020122.3353
Norwalk-like virus, outbreaks - UK (03) 20020130.3439
.................cp/pg/mpp
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