Published Date: 2004-01-29 23:50:00
Subject: PRO/AH> Avian influenza, poultry vaccines (02)
Archive Number: 20040129.0339
AVIAN INFLUENZA, POULTRY VACCINES (02)
A ProMED-mail post
ProMED-mail is a program of the
International Society for Infectious Diseases
Date: 27 Jan 2004
From: Dave Halvorson <email@example.com> [edited]
Regarding commentary on the use of H5N2 vaccine in an H5N1
1. About a year ago Hong Kong began vaccinating their poultry with
an inactivated H5 vaccine to protect against imported virus.
Recently (January 2004) Hong Kong began requiring all imported
poultry to be vaccinated with an inactivated H5 vaccine (BMJ 328,
17 Jan. p 123. 2004).
2. There is no live (licensed) AI vaccine.
3. The use of H5N2 as a vaccine to protect against H5N1 is
designed to differentiate infected from vaccinated animals (DIVA).
4. On the subject of vaccination, there ought to be a discussion on
how Hong Kong can use vaccine to protect its chickens against H5
influenza; WHO suggests suitable vaccine strains are lacking.
David A. Halvorson, DVM, ACPV
Extension Veterinarian - Avian Health
College Of Veterinary Medicine
University of Minnesota
1971 Commonwealth Avenue
Saint Paul, Minnesota, USA
[Dr Halvorson's comments are appreciated. The application of
avian influenza vaccines with a heterologous neuraminidase (not
N1, in the current case) is meant to enable their use as natural
"marker" vaccines or DIVA (differentiating infected from
vaccinated animals). This method has been advocated and applied
in recent years in several countries, initially Northern Italy; see
commentary in 20030428.1047, 20030429.1061. - Mod.AS]