Published Date: 2005-08-07 23:50:00
Subject: PRO/AH/EDR> Streptococcus suis, porcine, human - China (09): OIE
Archive Number: 20050807.2296

STREPTOCOCCUS SUIS, PORCINE, HUMAN - CHINA (09): OIE
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Date: 6 Aug 2005
From: ProMED-mail <promed@promedmail.org>
Source: OIE Disease Information, 5 Aug 2005, Vol. 18 - No. 31 [edited]
<http://www.oie.int/eng/info/hebdo/a_current.htm#Sec9>

Streptococcus suis in the People's Republic of China
-----------------------------------------------
Immediate notification report
Information received on 5 Aug 2005 from Mr. Jia Youling, Director
General, Veterinary Bureau, Ministry of Agriculture, Beijing:
Report date: 5 Aug 2005.
Reason for immediate notification: an emerging disease with
significant morbidity or mortality, or zoonotic potential (though
this is not a disease notifiable to the OIE).
Precise identification of agent: _Streptococcus suis_ B.
Date of 1st confirmation of the event: 25 Jul 2005.
Date of start of the event: 25 Jun 2005.
Nature of diagnosis: clinical, post-mortem and laboratory.
Details of outbreaks:
1st administrative division (province): Sichuan
Lower administrative division (city): Chengdu
Type of epidemiological unit: ...
Date of start of the outbreak: 2 Aug 2005
Species: sui
Number of animals in the outbreaks:
susceptible / cases / deaths / destroyed / slaughtered
19 / 15 / 1 / 19 / 0
1st administrative division (province): Sichuan
Lower administrative division (city): Deyang
Type of epidemiological unit: ...
Date of start of the outbreak: 29 Jul 2005
Species: sui
Number of animals in the outbreaks:
susceptible / cases / deaths / destroyed / slaughtered
66 / 5 / 5 / 66 / 0
1st administrative division (province): Sichuan
Lower administrative division (city): Luzhou
Type of epidemiological unit: ...
Date of start of the outbreak: 12 Jul 2005
Species: sui
Number of animals in the outbreaks:
susceptible / cases / deaths / destroyed / slaughtered
7 / 2 / 2 / 7 / 0
1st administrative division (province): Sichuan
Lower administrative division (city): Mianyang
Type of epidemiological unit: ...
Date of start of the outbreak: 24 Jul 2005
Species: sui
Number of animals in the outbreaks:
susceptible / cases / deaths / destroyed / slaughtered
1 / 1 / 1 / 1 / 0
1st administrative division (province): Sichuan
Lower administrative division (city): Nanchong
Type of epidemiological unit: ...
Date of start of the outbreak: 29 Jul 2005
Species: sui
Number of animals in the outbreaks:
susceptible / cases / deaths / destroyed / slaughtered
2 / 2 / 2 / 2 / 0
1st administrative division (province): Sichuan
Lower administrative division (city): Neijiang
Type of epidemiological unit: ...
Date of start of the outbreak: 15 Jul 2005
Species: sui
Number of animals in the outbreaks
susceptible / cases / deaths / destroyed / slaughtered
3159 / 193 / 0 / 3159 / 0
1st administrative division (province): Sichuan
Lower administrative division (city): Zigong
Type of epidemiological unit: ...
Date of start of the outbreak: 17 Jul 2005
Species: sui
Number of animals in the outbreaks:
susceptible / cases / deaths / destroyed / slaughtered
583 / 9 / 7 / 583 / 0
1st administrative division (province): Sichuan
Lower administrative division (city): Ziyang
Type of epidemiological unit: ...
Date of start of the outbreak: 25 Jun 2005
Species: sui
Number of animals in the outbreaks:
susceptible / cases / deaths / destroyed / slaughtered
2899 / 414 / 301 / 2899 / 0
Description of affected population: all infected pigs are in backyard farms.
Diagnosis:
*Laboratories where diagnosis was made: Sichuan Province General
Station of Animal Epidemics Prevention and Surveillance, Sichuan
Diagnostic tests used: isolation and culture of bacterium
Date: ...
Results: positive
*Laboratories where diagnosis was made Foreign Animal Disease
Diagnosis Centre, National Animal Quarantine Institute, Qingdao
Diagnostic tests used: microscopy
Date: ...
Results: positive
Diagnostic tests used: fluorescent antibody test
Date: ...
Results: positive
*Laboratories where diagnosis was made: Harbin Veterinary Research
Institute, Chinese Academy of Agricultural Sciences, Harbin
Diagnostic tests used: PCR(1)
Date: 25 Jul 2005
Results: positive
Diagnostic tests used: sequencing
Date: ...
Results: the pathogen, _Streptococcus suis_ B, shares 98 percent
nucleotide homology with the CPS2 gene of the AF118389 strain of the
GenBank databank
Note: The Foreign Animal Disease Diagnosis Centre and the Harbin
Veterinary Research Institute carried out a differential diagnosis.
Using RT-PCR(2) with type A influenza virus as positive control and
RT-PCR(2) for Nipah virus, the results were negative. The results of
pathogen isolation by SPF egg inoculation and pathogen isolation on
VERO cell line, after 2 passages, were also negative. Avian influenza
and Nipah disease were, therefore, excluded.
Source of outbreaks or origin of infection: unknown or inconclusive.
Control measures
A. Undertaken:
- Stamping out.
- Quarantine (lifting of quarantine: 14 days after the last pig was culled).
- Movement control inside the country.
- Screening.
- Zoning. Premises with infected pigs or relevant slaughterhouses and
other facilities are considered as infected points; areas within a
one km radius are considered as infected zones; areas within 3 km
around the infected zones are considered as buffer zones.
- Disinfection of infected premises/establishments.
- Dipping/spraying.
- Sichuan province has organized a general survey for 51 880 300 live
pigs (87.92 percent of the pig population in the province).
B. To be undertaken: vaccination. An inactivated _Streptococcus suis_
vaccine is being tested in the field. All pigs in the infected zones
and buffer zones will be vaccinated if the experiment is successful.
Treatment of affected animals: no.
(1) PCR: polymerase chain reaction
(2) RT-PCR: reverse transcriptase - polymerase chain reaction
--
ProMED-mail
<promed@promedmail.org>
[It is most helpful to have these complete laboratory results and
some recent epidemiological information. We look forward to similar
reports in the near future, as there is much to be learned from this
outbreak. - Mod.PC]
[In the report, the number of susceptible animals is identical to the number
of destroyed animals. Dead animals should not be counted within the
destroyed animals. - Mod.AS]

See Also

Streptococcus suis, porcine, human - China (08): OIE 20050805.2285
Streptococcus suis, porcine, human - China (07) 20050804.2271
Streptococcus suis, porcine, human - China (06) 20050804.2266
Streptococcus suis, porcine, human - China (05) 20050803.2262
Streptococcus suis, porcine, human - China (04) 20050803.2250
Streptococcus suis, porcine, human - China (03) 20050802.2246
Streptococcus suis, porcine, human - China (02) 20050801.2238
Streptococcus suis, porcine, human - China 20050730.2217
Streptococcus suis, human - China (Hong Kong) 20050728.2196
Streptococcus suis, porcine, human - China (Sichuan)(02) 20050728.2194
Streptococcus suis, porcine, human - China (Sichuan) 20050727.2179
Undiagnosed deaths - China (Sichuan)(05): Strep. suis susp. 20050726.2169
Undiagnosed deaths - China (Sichuan)(04): Strep. suis susp. 20050726.2160
Undiagnosed deaths - China (Sichuan) (03) 20050725.2153
Undiagnosed deaths - China (Sichuan) (02) 20050724.2139
Undiagnosed deaths - China (Sichuan): RFI 20050724.2131
............pc/msp/lm
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