Published Date: 2007-07-12 23:50:00
Subject: PRO/MBDS> Dengue - Viet Nam (10): DEN-1, DEN-2, DEN-3
Archive Number: 20070712.2226
DENGUE - VIET NAM (10): DEN-1, DEN-2, DEN-3
A ProMED-mail post
ProMED-mail is a program of the
International Society for Infectious Diseases
Date: Thu 12 Jul 2007
Source: Thanh Nien Daily [edited]
Viet Nam's 29 000 dengue infections this year  mark a 30
percent jump over the same period last year .
Nguyen Van Binh, deputy head of the Health Ministry's Center for
Preventive Healthcare, said the mosquito-borne outbreak would
continue. This year  could be the worst year on record as hot
weather and rising rainfall have created thriving mosquito
populations that spread the disease.
Additionally, the type of dengue people are contracting has changed
recently. In the 1999-2006 period, patients were infected mainly by
DEN-3 (Dengue 3) and DEN-2 (Dengue 2) [serotypes].
However, this year , serum tests have showed that 58 percent of
cases contracted DEN-1 while the other 42 percent have tested
positive for all 3 types of the fever [do they mean that 42 percent
have tested positive for the other 2 types of dengue virus or that
mixed infections were identified with all 3 virus types implicated?
This moderator chooses to interpret this as meaning that the other 2
serotypes were involved in 42 percent of the cases, highlighting that
all 3 serotypes are circulating simultaneously in Viet Nam - Mod.MPP].
DEN-1 causes serious complications like hemorrhages, carditis, and
liver problems. Tran Ngoc Huu, head of the Ho Chi Minh City-based
Pasteur Institute, said infections have risen as people have yet to
acquire any immunity to DEN-1.
According to statistics, Viet Nam is recording 3000 new dengue
infections every week, an increase of over 33.3 percent year-on-year.
The majority of patients are in the southern provinces, especially
the Mekong Delta region. Ho Chi Minh City has seen about 2000 dengue
infections this year .
Le Thi Bich Lien from the HCMC Pediatrics Hospital Number 1 said the
hospital receives some 20 cases daily.
According to the city's Pediatrics Hospital Number 2, the number of
its dengue patients over the last 6 months has been nearly equal to
last year's  total number. Everyday, 15-20 dengue cases are
Meanwhile, the Mekong Delta region has been the worst hit due to the
complex systems of rivers and streams where mosquitoes breed.
Dong Thap province has reported that over 400 patients were
hospitalized last week [2-8 Jul 2007], raising the total number of
infections to 4400 in the 1st half of the year . Similar
numbers have been reported in Tien Giang province. Kien Giang
province has recorded over 3100 cases, according to the provincial
Preventive Healthcare Center. In Soc Trang province, the number has
been nearly 2800.
Standing Deputy Prime Minister, Nguyen Sinh Hung, has directed the
ministry to cooperate with local health watchdogs and authorities to
quickly stamp out the epidemic.
Last week [2-8 Jul 2007], the ministry held a conference with
authorities from 20 of the countries worst hit localities to discuss
measures to control the epidemic.
The disease has also struck a number of other Southeast Asian
countries this year , including Cambodia, Malaysia, Singapore,
[The newswire above mentions the profile of the serotypes of dengue
virus involved in this year's (2007) epidemic in Viet Nam. There are
4 known serotypes of dengue virus -- DEN-1, DEN-2, DEN-3 and DEN-4.
While it does appear that DEN-1 is a "new kid" on the block in Viet
Nam, it should be noted that DEN-2 and DEN-3 are still circulating
and are responsible for approximately 42 percent of the cases tested
this year (if the figures presented in the newswire are correct).
For an excellent review of dengue, please see Gubler DJ: Dengue and
Dengue Hemorrhagic Fever; Clin Microbiol Rev. 1998 July; 11(3):
480-496. The full chapter is available at
and is an excellent review article on all aspects of dengue fever,
with an extensive bibliography for those who wish to research this topic more.
For maps of Viet Nam with provinces, see