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Archive Number 20100131.0335
Published Date 31-JAN-2010
Subject PRO/EDR> Tuberculosis, drug resistance - Marshall Islands: RFI

TUBERCULOSIS, DRUG RESISTANCE - MARSHALL ISLANDS: REQUEST FOR INFORMATION
*************************************************************************
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Date: Sat 30 Jan 2010
Source: Top News [edited]
<http://topnews.us/content/210458-tb-health-emergency-marshall-islands>


A public health emergency has been declared in Marshall Islands. This 
has happened following an outbreak of drug-resistant tuberculosis 
(TB). The government is thinking of calling upon special powers of quarantine.

In less than 2 months the number of people with the drug-resistant 
disease has risen from 6 to 10 in the western Pacific nation. 
Everyone now fears that the situation would escalate and will reach 
to 500. Majuro Hospital chief of staff Marie Lanwi-Paul, said, "We 
are in the process of doubling the bed capacity" in the TB isolation unit."

Rachel Powel who is working with the World Health Organisation said, 
"Drug resistance poses a serious threat to our ability to treat and 
control TB." Marshall Islands Health Minister Amenta Matthew said she 
was in the process of forming legislation that would give power to 
the director of health to quarantine people who were not complying 
with TB prevention requirements. Matthew felt that the drug-resistant 
TB evolved because of people not following advice of taking medicines 
despite physicians counseling them. It was reported that one patient 
was taken to the court by health authorities for failing to take 
treatment and remain in isolation.

[Byline: Anjali Singh]

--
Communicated by:
M. Randolph Kruger
<memphisservices@bellsouth.net>

[It is stated in the news release that the outbreak of drug resistant 
TB in the Marshall Islands is secondary to improper management of the 
TB cases, i.e., the TB drugs were not taken by patients as 
recommended by the physicians. However, the exact drugs to which the 
_Mycobacterium tuberculosis_ isolates are resistant and the extent of 
the drug resistance is not specified in the above news release. Also 
it is not specified if there is any epidemiological linkage among the 
patients, if the isolates have similar drug resistance patterns, or 
if they have been genotyped. Detailed discussions of drug-resistant 
TB can be found in prior ProMED posts below.

The Marshall Islands is an island nation with a population of about 
62 000 in the middle of the Pacific Ocean, just west of the 
International Date Line and just north of the Equator 
(<http://en.wikipedia.org/wiki/Island_nation>). From 1946 to 1958, 
the USA tested 67 nuclear weapons in the Marshall Islands. 
Independence was completed in 1990, when the UN officially ended its 
Trusteeship status. In 1986, the Compact of Free Association with the 
USA provides for aid and USA defense of the islands in exchange for 
continued USA military use of a missile testing range 
(<http://en.wikipedia.org/wiki/Island_nation>). The location of the 
Marshall Islands in relation to other countries in the South Pacific 
can be found on a map at
<http://www.lonelyplanet.com/maps/pacific/>. - Mod.ML]

[see also:
2009
----
Tuberculosis, XXDR - USA: FL ex Peru  20091230.4387
Tuberculosis, MDR - China  20090114.0151
2008
---
Tuberculosis, XDR - Austria ex Romania  20080803.2373
Tuberculosis, MDR, XDR - Peru  20080412.1337
Tuberculosis, XDR - Namibia  20080403.1231
Tuberculosis, XDR - UK (Scotland) ex Somalia  20080322.1094
Tuberculosis, MDR, XDR - Worldwide: WHO  20080228.0813
Tuberculosis, MDR - South Africa  20080208.0521
Tuberculosis, MDR - Papua New Guinea  20080206.0478
Tuberculosis, XDR - Botswana, South Africa  20080118.0222
2007
----
Tuberculosis, XDR, MDR: genome sequences  20071122.3780
Tuberculosis - Uganda (02): MDR, susp. RFI  20071004.3284
Tuberculosis - Uganda: deadly strain, RFI  20071002.3255
Tuberculosis, XDR - South Africa (11): fugitives  20071002.3251
Tuberculosis, XDR - South Africa (10): Western Cape  20070627.2071
Tuberculosis, XDR - worldwide (02)  20070623.2034
Tuberculosis, XDR - South Africa (09): Western Cape  20070604.1805
Tuberculosis, XDR, airplane exposure - multicountry (03)  20070601.1778
Tuberculosis, XDR, airplane exposure - multicountry (USA, France, 
Canada, Czech Rep.)  20070529.1738
Tuberculosis, XDR - South Africa (08): Western Cape  20070425.1349
Tuberculosis, XDR, 2003-2006 - Europe (Germany, Italy)  20070403.1132
Tuberculosis, XDR - South Africa (07): Eastern Cape  20070326.1044
Tuberculosis, XDR, 1993-2006 - USA  20070322.1005
Tuberculosis, XDR - South Africa (06)  20070319.0959
Tuberculosis, XDR, 1991-2003 - Spain  20070302.0738
Tuberculosis, XDR - South Africa (05)  20070228.0717
Tuberculosis, XDR - South Africa (04)  20070220.0638
Tuberculosis, XDR - South Africa (03)  20070209.0504
Tuberculosis, XDR - worldwide  20070205.0456
Tuberculosis, XDR - South Africa (02)  20070128.0375
Tuberculosis, XDR - South Africa: interventions  20070126.0349]
............................................ml/ejp/dk

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