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Archive Number 20090303.0871
Published Date 03-MAR-2009
Subject PRO/AH/EDR> Kyasanur forest disease - India (02): (KA)

KYASANUR FOREST DISEASE - INDIA (02): (KARNATAKA)
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Date: Tue 3 Mar 2009
From: Steve Berger <mberger@post.tau.ac.il>


Re: Kyasanur forest disease vaccine
-----------------------------------
Regarding Kyasanur forest disease (KFD), an effective and safe
vaccine has been available for over 15 years. 88 152 persons were
immunized in trials during 1990 to 1992, with no report of adverse
effects. The formalin-inactivated vaccine is prepared from tissue
culture, and administered at a dose of 1.0 ml subcutaneously (0.5 ml
below age 6), with a booster dose after 4 weeks.

The geographic distribution of this group of viruses is not
restricted to Karnataka. For example, 22.4 percent of persons living
in the Andaman and Nicobar Islands were found to be seropositive
for KFD in 2002; and human infection by closely related agents is
reported in Saudi Arabia (Alkhurma virus) and China (Nanjianyin
virus).

[Source: Gideon (Global Infectious Disease & Epidemiology Network)
<http://www.gideononline.com/blog/2009/03/02/kyasanur-forest-disease/>.]

--
Dr Steve Berger
Geographic Medicine
Tel Aviv Medical Center
Israel
<mberger@post.tau.ac.il>

[ProMED-mail is indebted to Professor Berger for his prompt response
to the request for information on Kyasanur forest disease vaccine.

See also: Dandawate CN, Desai GB, Achar TR, Banerjee K: Field
evaluation of formalin inactivated Kyasanur forest disease virus
tissue culture vaccine in three districts of Karnataka state. Indian
J Med Res. 1994 Apr; 99: 152-8; abstract available at
<http://www.ncbi.nlm.nih.gov/pubmed/7927566>. - Mod.CP]

[CDC may wish to update its page on KFD regarding geographic  
distribution and availability of a vaccine. - Mod.JW]

[see also:
Kyasanur forest disease - India (KA) 20090302.0860
2006
----
Kyasanur Forest disease - India (03): background 20060216.0510
Kyasanur Forest disease - India (02): background 20060120.0187
Kyasanur Forest disease - India: susp 20060118.0162
2004
----
Alkhurma virus, human death - Saudi Arabia (02) 20040309.066
Alkhurma virus, human death - Saudi Arabia 20040302.0631
Undiagnosed illness - India (Karnataka) (02): Kyasanur Forest: corr.
20040425.1145
Undiagnosed illness - India (Karnataka) (02): Kyasanur Forest
disease: conf. 20040424.1135
2003
----
Kyasanur Forest disease - India (Karnataka) (02) 20030606.1391
Kyasanur Forest disease - India (Karnataka) 20030503.1106
2000
----
Kyasanur forest disease - India (Western Ghats) 20000506.0692
Kyasanur Forest disease - India (02) 20000415.0536
Kyasanur Forest Disease - India: background 20000323.0413
Kyasanur Forest Disease - India 20000322.0411
1998
----
Kyasanur Forest disease - India: Background 19981220.2416
Kyasanur Forest disease, suspected - India 19981217.2390]
........................................cp/mj/jw
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