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Archive Number 20090615.2220
Published Date 15-JUN-2009
Subject PRO/AH> Influenza A (H1N1): animal health (14), EU preparedness, Egypt
INFLUENZA A (H1N1): ANIMAL HEALTH (14), EU PREPAREDNESS, EGYPT
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[1]
Date: Mon 15 Jun 2009
Source: EFSA website [edited]
<http://ec.europa.eu/food/animal/diseases/influenzaAH1N1/docs/Conclusions_AH1N1_090609.pdf>


Brainstorming of scientists, risk assessors and risk managers on the 
novel A(H1N1) influenza virus at the human animal interface; "What 
needs to be done in Europe in the next months?;" Brussels, 9 Jun 2009
-----------------------------------------------
Conclusions of the Commission assisted by EFSA and ECDC.

1. It is expected that the novel influenza virus A(H1N1) will 
continue to circulate and spread in the human population in Europe in 
the coming months, in particular in autumn and winter.

2. Probable human-to-pig transmission of the novel virus has been 
described on one occasion in Canada, and experiments in Europe have 
shown that the pigs are susceptible to the novel virus [The 
human-to-pig transmission in Canada has been put in doubt; see 
20090615.2215. - Mod.AS].

3. Given the continued spread of this novel virus in the human 
population, the risk of it entering pig farms in Europe will, 
therefore, increase in the next months.

4. From an animal health perspective, current evidence from the 
single field outbreak and findings from experimental studies suggest 
that this novel virus in its current form is unlikely to cause more 
significant health problems in pigs than those already seen by the 
swine influenza viruses circulating in pigs in Europe, which is 
self-limiting infection of the respiratory tract with some morbidity 
but generally leading to uneventful recovery.

5. From a human health perspective, the direct and indirect 
human-to-human routes of transmission will continue to pose the 
highest risk and account for all human infections. A sustained 
circulation of this virus in pigs may pose an additional risk for 
transmission to humans for people in close contact with infected pigs.

6. However, swine influenza is not a food-borne zoonosis. Moreover, 
there is no evidence suggesting that this novel virus behaves in a 
different way from the other swine influenza viruses and spreads to 
humans via food containing pork or pork products. With regard to 
infection of pigs via feeding, account should be taken of the 
intra-species feeding ban. This is also supported by the initial data 
on experimental infection of piglets that have become available in 
recent weeks, indicating infection of only the respiratory tract and 
no other tissues and absence of detectable viraemia. Therefore, the 
recommendations issued by the relevant European and international 
organizations adequately address the issue of food safety in relation 
to influenza.

7. The measures to be taken on pig farms addressing human-to-pig 
transmission, pig-to-pig transmission and pig-to-human transmission 
should be proportionate to: 1) the risk posed by pigs in the 
transmission of the novel virus to humans, if any, compared to the 
role played by human-to-human transmission, 2) the severity of 
disease in animals and humans, and 3) risk factors in humans.

8. The most important measure for reducing the risk of human-to-pig 
transmission is the implementation of bio-security measures on pig 
farms aimed in particular at reducing the risk that people infected 
with the novel influenza are in contact with pigs.

9. However, over and above the seasonal vaccination against influenza 
in human, vaccination of staff working in contact with pigs to 
protect against the novel virus, when specific vaccines are 
available, should be considered by authorities as a possible 
additional measure to reduce the risk of virus circulation between 
humans and pigs.

10. Vigilance on possible circulation of the novel virus in pig farms 
should be enhanced.

11. Surveillance for the novel virus in pig farms should: 1) in the 
context of risk management, focus on timely detection of virus on 
farms with a known risk of human-to-pig transmission; and 2) in the 
context of risk assessment and research, be aimed at improving our 
understanding of the risk of possible circulation of virus in pig 
farms and its possible impact on public health and also monitor its 
further evolution.

12. If surveillance activities based on investigations and sampling 
are carried out in pig farms in order to detect the novel virus, they 
should be focused on pigs that potentially have been exposed to 
infected humans and those showing respiratory signs.

13. The data generated by the surveillance/monitoring activities of 
the ESNIP project have been very informative and useful, and the 
activities should be continued and intensified.

14. The veterinary and public health authorities in the Member States 
should ensure that adequate information is provided to pig farmers, 
private veterinarians, and general practitioners on the prevention 
and surveillance measures above and that the veterinary laboratories 
have the necessary diagnostic capability.

15. It is too early at this stage to envisage a role of vaccines in 
the prevention and control of the novel virus in pigs.

16. In case novel virus is detected on a pig farm, proportionate 
measures to protect humans from this occupational risk should be 
implemented, particularly for persons most likely to experience 
severe disease.

17. Measures to be taken on pig farms in the next months should, 
however, be flexible, allowing an adaptation to a possible further 
evolution of the virus and to its transmission patterns.

18. It is highly desirable that in the EU the initiatives of all 
stakeholders, including risk assessors, risk managers and 
researchers, be coordinated so that joint efforts result in a more 
efficient achievement of the objectives. This should in particular 
include information exchange on collection and analysis of data, 
identification of gaps for research, and formal risk assessment.

19. The guidelines that the relevant international organizations are 
preparing on biosecurity and surveillance on pig farms will help to 
shape the EU response to this potential threat.

--
Communicated by:
ProMED-mail <promed@promedmail.org>

[The other documents presented or produced during the "brainstorming 
meeting" in Brussels on 9 Jun 2009 can be accessed online at
<http://ec.europa.eu/food/animal/diseases/influenzaAH1N1/index_en.htm>.
The presentations include, among other things, animal experiments 
with the new virus (Pathogenesis and Transmission Studies) carried 
out by the EU, Canada and the USA. - Mod.AS]

******
[2]
Date: Mon 15 Jun 2009
From: Diaa Elyan <diaa.elyan.ctr.eg@med.navy.mil>


We have learned that different influenza A viruses known to cause 
disease in humans have recently been isolated/detected in pigs; e.g. 
China [H3N2, H5N1], Indonesia [H5N1], Canada [H1N1]. Interestingly, 
most of those cases were either classified as either mild infections 
or even have passed without significant illness.

To better understand the implications of these findings, researchers 
around the globe have engaged in performing detailed surveillance in 
pigs in locations where all or some of the said strains are reported. 
Scientists have also expressed interest in conducting some lab 
experiments to understand the probability of virus genetic 
exchange/reassortment and possible pathogenicity and the role of pigs 
as mixing vessels/pathways for emergence of a potential pandemic 
strain.

Have those researchers who isolated/detected the above mentioned 
influenza virus isolates in pigs published the genetic analysis and 
discussed their relatedness to human and/or avian strains?

--
Communicated by:
Diaa Elyan
CTR EG NAMRU3, Cairo, Egypt
<diaa.elyan.ctr.eg@med.navy.mil>

[A valid question, especially within the One Health concept. Some of 
the sought information is included in the presentations discussed in 
item 1. Responses will be welcomed.

It will also be interesting to note whether NAMRU3 has been involved 
in testing pigs for influenza A viruses in Egypt. - Mod.AS]


*****
[3]

Date: 12 Jun 2009
Source: EarthTimes
<http://www.earthtimes.org/articles/show/272912,egypt-hunts-last-pigs-as-three-new-swine-flu-cases-confirmed.html>

Egypt hunts last pigs as three new swine flu cases confirmed
----------------------------------------
As the number of confirmed cases of the A(H1N1), or swine flu, virus 
continued to climb in Egypt, the government vowed to redouble its 
efforts to hunt down the country's last surviving pigs. Assistant 
Health Minister Nasr al-Sayid on Friday confirmed three new cases of 
the disease, which the World Health Organization on Thursday labelled 
a global pandemic.

Al-Sayid said the three new cases had come from Canada, Sweden, and 
the United States, and that they had been taken to hospital for 
isolation and treatment, Egypt's official Middle East News Agency 
(MENA) reported Friday.

The Ministry of Health said the three cases brought the total number 
of confirmed cases of swine flu in Egypt to 15.

As new confirmed infections continued to trickle in, the Egyptian 
government redoubled its efforts to hunt down the country's last 
remaining pigs.

Hamid Samaha, the head of Egypt's General Authority for Veterinary 
Services, on Friday said government inspectors had found two 
surviving pigs in Giza, just across the river from Cairo. The pigs 
were culled on the spot, MENA reported.

Samaha said the government had so far killed 15,000 pigs, and that it 
expected to kill all remaining Egyptian swine by the end of next week.

He added the government would vaccinate 60 million fowl as part of 
its campaign against the related H5N1, or bird flu, virus.

Last week, a four-year-old girl from the Nile Delta province of 
Daqahliya became the 27th person to die of bird flu in Egypt. Hers 
was the 72nd confirmed case of that virus in the country, MENA said.
--
Communicated by:
Pacific Veterinary List
<pacvet@lyris.spc.int>

[see also:
Influenza A (H1N1): animal health (13) swine, Canada, origin, RFI 20090615.2215
Influenza A (H1N1): animal health (12) swine trial inf. 20090605.2088
Influenza A (H1N1): animal health (11) swine trial inf. 20090604.2067
Influenza A (H1N1): animal health (10) swine, Canada, cull 20090514.1813
Influenza A (H1N1): animal health (09), swine, Canada 20090513.1790
Influenza A (H1N1): animal health (08), food safety, FAO/OIE/WHO 20090507.1710
Influenza A (H1N1): animal health (07), swine, Canada, OIE 20090506.1691
Influenza A (H1N1): animal health (06), Canada, OIE 20090505.1683
Influenza A (H1N1): animal health (05), swine, Canada, FAO 20090505.1680
Influenza A (H1N1): animal health (04), infected swine, Canada 20090502.1653
Influenza A (H1N1): animal health (03), Egypt, pig cull 20090502.1649
Influenza A (H1N1): animal health 20090430.1637
Influenza A (H1N1), "swine flu": animal health (02), Egypt, 
prevention 20090429.1623
Influenza A (H1N1), "swine flu": animal health 20090428.1604]
......................................................arn/msp/lm

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