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Archive Number 20080922.2988
Published Date 22-SEP-2008
Subject PRO> Influenza vaccine 2009: S. hemisphere
INFLUENZA VACCINE 2009: SOUTHERN HEMISPHERE
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A ProMED-mail post
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International Society for Infectious Diseases
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Date: Mon 22 Sep 2008
Source: World Health Organisation (WHO), EPR, Influenza [edited]
<http://www.who.int/csr/disease/influenza/recommendations2009south/en/index.html>


Recommended composition of influenza virus vaccines for use in the 
2009 southern hemisphere influenza season
-----------------------------------------------
It is recommended that vaccines for use in the 2009 influenza season 
(southern hemisphere winter) contain the following:

- an A/Brisbane/59/2007 (H1N1)-like virus;*
- an A/Brisbane/10/2007 (H3N2)-like virus;**
- a B/Florida/4/2006-like virus.***

*A/South Dakota/6/2007 (an A/Brisbane/59/2007-like virus) is a 
current vaccine virus used in live attenuated vaccines.
**A/Brisbane/10/2007 and A/Uruguay/716/2007 (an 
A/Brisbane/10/2007-like virus) are current vaccine viruses.
***B/Florida/4/2006 and B/Brisbane/3/2007 (a B/Florida/4/2006-like 
virus) are current vaccine viruses.

--
Communicated by:
ProMED-mail <promed@promedmail.rg>

[Background: Twice annually, the WHO Global Influenza Programme 
analyses the global data on circulating influenza strains and issues 
recommendations on the formulation of the influenza vaccine for the 
following influenza season. These recommendations are used by the 
national drug licensing agencies and the pharmaceutical companies to 
update the content of the influenza vaccines they produce. An annual 
adjustment of the vaccine content is necessary to match the vaccine 
with the ever changing antigenic and genetic characteristics of 
circulating influenza viruses.

In August 2008, the United States Food and Drug Administration's 
Vaccines and Related Biological Products Advisory Committee (see: 
ProMED-mail post "Influenza vaccine 2008/2009 - N. hemisphere 
20080805.2404") recommended that vaccines to be used in the 2008-2009 
influenza season in the U.S. contain the following:

- an A/Brisbane/59/2007 (H1N1)-like virus;
- an A/Brisbane/10/2007 (H3N2)-like virus;*
- a B/Florida/4/2006-like virus.**

*A/Brisbane/10/2007 is a current southern hemisphere vaccine virus.
**B/Florida/4/2006 and B/Brisbane/3/2007 (a B/Florida/4/2006-like 
virus) are current (2007/2008) southern hemisphere vaccine viruses.

The influenza vaccine composition to be used in the 2008-2009 
influenza season in the U.S. is identical to that recommended by the 
World Health Organization on 14 Feb 2008 for the Northern 
Hemisphere's 2008-2009.

In summary, perhaps unusually, the composition of the influenza 
vaccines for use in the northern and southern hemispheres in 2009 are 
identical. - Mod.CP]

[see also:
Influenza vaccine 2008/2009 - N. hemisphere 20080805.2404
Influenza virus, vaccine response: RFI 20080209.0528
Influenza, pediatric mortality: CDC notice 20080202.0426
Influenza virus, 2007/2008 vaccine mismatch 20080209.0529
2007
----
Influenza update - USA & worldwide 20070928.3217
Influenza: update & vaccine composition 20070810.2607
2006
----
Influenza vaccine 2006/2007 - N hemisphere 20060303.0676]
....................................cp/msp/mpp

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