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INFLUENZA A (H1N1) - WORLDWIDE (85): TAMIFLU RESISTANCE, JAPAN
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A ProMED-mail post
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International Society for Infectious Diseases
<http://www.isid.org>
Date; Mon 6 Jul 2009
Source: The Japan Times online [edited]
<http://search.japantimes.co.jp/rss/nn20090706a6.html>
The Osaka Prefectural Government sent a research paper to a U.S.
medical journal on the 1st case in Japan of a genetic mutation of
swine flu [virus] resistant to Tamiflu about a week before making the
finding public, officials said Sunday [5 Jul 2009]. "It's not that we
intentionally placed priority on the manuscript and delayed the
announcement," said Tatsuya Oshita, an official in the prefectural
government's health and medical care department. "As it turned out, we
dealt with the matter in a way that could be criticized, and we are
sorry."
The H1N1 virus resistant to Tamiflu was found in a woman in her 40s in
Osaka Prefecture on 18 Jun 2009 -- 2 weeks before the announcement --
through virus sample analysis at the Osaka Prefectural Institute of
Public Health, the officials said. A staff member of the institute
submitted a manuscript on the analysis result to the U.S. journal on
24 Jun 2009, but it had not been run in the magazine as of Sunday [5
Jul 2009], the officials said.
The prefectural government reported the case to the Health, Labor and
Welfare Ministry last Wednesday, a week after it sent the manuscript
to the U.S. journal, and held a news conference the next day to make
it public based on advice from the ministry, the officials said. The
prefectural government had said its report to the ministry was delayed
because it took some time to study the methods for examining
abnormalities in viruses.
--
Communicated by:
Motoi Suzuki, MD
MSc Public Health in Developing Countries candidate
London School of Hygiene and Tropical Medicine, UK
<motoi.suzuki@gmail.com>
[The oseltamivir resistant influenza virus A(H1N1)v seems to have been
detected more than 2 weeks ago in Japan. The reason for the delay in
release of this information is unclear.
Osaka in the Kansai region of the main island of Honshu can be located
in the HealthMap/ProMED-mail interactive map of Japan at
<http://healthmap.org/r/00v7>. - Mod.CP].
[see also:
Influenza A (H1N1) - worldwide (84): Tamiflu resistance, China (HK)
20090706.2428
Influenza A (H1N1) - worldwide (83): antiviral resistance 20090705.2417
Influenza A (H1N1) - worldwide (82): transmission 20090704.2402
Influenza A (H1N1) - worldwide (81): epidemic analysis 20090703.2391
Influenza A (H1N1) - worldwide (80): Argentina, human to pig 20090701.2376
Influenza A (H1N1) - worldwide (79): case count 20090701.2372
Influenza A (H1N1) - worldwide (78): Tamiflu resistance, DK 20090630.2359
Influenza A (H1N1) - worldwide (76): comments on 1918 virus (03) 20090625.2309
Influenza A (H1N1) - worldwide (74): susp. origin 20090624.2303
Influenza A (H1N1) - worldwide (73): case count, epidemiology 20090622.2288
Influenza A (H1N1) - worldwide (72): case count, epidemiology 20090619.2261
Influenza A (H1N1) - worldwide (70): risk factors 20090619.2260
Influenza A (H1N1) - worldwide (69): other viral infections 20090618.2254
Influenza A (H1N1) - worldwide (68): southern hemisphere 20090618.2253
Influenza A (H1N1) - worldwide (65): antivirals in pregnancy 20090616.2224
Influenza A (H1N1) - worldwide (64): case count, pandemic 20090616.2221
Influenza A (H1N1) - worldwide (62): Egypt, Lebanon 20090611.2150
Influenza A (H1N1) - worldwide (62): Egypt, Lebanon 20090611.2150
Influenza A (H1N1) - worldwide (60): Egypt (Cairo) 20090608.2117
Influenza A (H1N1) - worldwide (59): Worldwide 20060608.2117
Influenza A (H1N1) - worldwide (58): USA, Africa 20090607.2109
Influenza A (H1N1) - worldwide (57): Brazil, USA 20090605.2090
Influenza A (H1N1) - worldwide (55) 20090603.2056
Influenza A (H1N1) - worldwide (47): China, epidemiology 20090526.1962
Influenza A (H1N1) - worldwide (45) 20090525.1951
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Influenza A (H1N1) - worldwide (31) 20090516.1835
Influenza A (H1N1) - worldwide (29) 20090515.1824
Influenza A (H1N1) - worldwide (26) 20090514.1798
Influenza A (H1N1) - worldwide (23) 20090511.1764
Influenza A (H1N1) - worldwide (21) 20090510.1749
Influenza A (H1N1) - worldwide (19) 20090509.1733
Influenza A (H1N1) - worldwide (17) 20090508.1722
Influenza (H1N1) - worldwide (15) 20090507.1709
Influenza A (H1N1) - worldwide (13) 20090506.1695
Influenza A (H1N1) - worldwide (11): coincident H3N2 variation 20090505.1679
Influenza A (H1N1) - worldwide 20090430.1636
Influenza A (H1N1) "swine flu": worldwide (07), update, pandemic 5
20090429.1622
Influenza A (H1N1) "swine flu": Worldwide 20090427.1583
Influenza A (H1N1) virus, human: worldwide 20090426.1577
Influenza A (H1N1) virus, human - New Zealand, susp 20090426.1574
Influenza A (H1N1) virus, human - N America (04) 20090426.1569
Influenza A (H1N1) virus, human - N America 20090425.1552
Acute respiratory disease - Mexico, swine virus susp 20090424.1546
Influenza A (H1N1) virus, swine, human - USA (02): (CA, TX) 20090424.1541
Influenza A (H1N1) virus, swine, human - USA: (CA) 20090422.1516
Influenza A (H1N1) virus, swine, human - Spain 20090220.0715]
......................................................cp/msp/jw
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